1. Research Infrastructures
  2. ITC Isothermal Titration Calorimeter MicroCal PEAQ

ITC Isothermal Titration Calorimeter MicroCal PEAQ

Offering main image The MicroCal PEAQ-ITC Isothermal Titration Calorimeter is a high-sensitivity instrument used to measure the thermodynamics of molecular interactions. It directly quantifies the heat released or absorbed during a binding event, providing in a single experiment all key parameters: binding affinity (Kᴰ), stoichiometry (n), enthalpy (ΔH), and entropy (ΔS) — without the need for labeling or immobilization. This technique allows detailed characterization of chemical and biomolecular interactions, including those involving small molecules, proteins, antibodies, nucleic acids, lipids, metal ions, and carbohydrates. It supports structure–activity relationship (SAR) studies, enzyme kinetics, inhibition analyses, and the investigation of self-assembly processes and nanomaterial interactions.

Name

ITC Isothermal Titration Calorimeter MicroCal PEAQ

Scientific domain

Chemistry


 

Biology


 

Biotechnology


Keywords

Scientific Collaboration


 

Technology Transfer


Home partner institution

University of Parma


Website

https://scvsa-servizi.campusnet.unipr.it/do/dotazioni.pl/Show?_id=9xhk

Equipment

High-sensitivity isothermal microcalorimeter with fully automated titration system; Precision syringe for controlled ligand injections; Dual-cell design with reference and sample cells maintained at constant temperature; Integrated PEAQ software suite for data acquisition and thermodynamic analysis; Suitable for biochemical, biophysical, and nanomaterial research applications;

Online booking system details

Bookable with supervisor approval professor Alessandro Pedrini (alessandro.pedrini@unipr.it); The instrument can be booked in 4-hour blocks (half-day) at a cost of €10 for SCVSA Department staff and €12 for authorized staff from other University departments.

Online booking system available

Yes