AF2000 Postnova – Asymmetric Flow Field-Flow Fractionation (AF4)

The AF2000 (Postnova Analytics) is an Asymmetric Flow Field-Flow Fractionation (AF4) system enabling separation and analysis of nanoparticles, macromolecules, or polymers based on hydrodynamic size; this stationary phase-free method preserves sample integrity with gentle separation in a thin channel; the system can be coupled with detectors (UV, MALS, DLS, RI) for highly precise online characterization (size, mass, conformation, absorbance, fluorescence), suitable for complex media or sensitive formulations; it also includes a preparative channel and fraction collector for producing purified fractions (~10 mg) at concentrations suitable for in vitro experiments (e.g., toxicity studies).

Name

AF2000 Postnova – Asymmetric Flow Field-Flow Fractionation (AF4)

Scientific domain

Nanomedicine


 

Colloid science


 

Pharmaceutical analysis


Keywords

Nanoparticles


 

AF4


 

Separation


Home partner institution

University of Angers


Technical staff available

Yes

Equipment

Asymmetric Flow Field-Flow Fractionation System (AF4) – Postnova Analytics AF2000